Publications

The effects of anti-fibrinolytic drugs in patients with or at risk of bleeding: a protocol for a systematic review and individual patient data meta-analysis

WHO recommendation on tranexamic acid for the treatment of postpartum haemorrhage – Highlights and Key Messages

WHO Team

Maternal, Newborn, Child & Adolescent Health & Ageing (MCA), Sexual and Reproductive Health and Research (SRH)

Red Blood Cell Transfusion and Mortality in Trauma Patients: Risk-Stratified Analysis of an Observational Study

Pablo Perel, Tim Clayton, Doug G. Altman, Peter Croft, Ian Douglas, Harry Hemingway, Aroon Hingorani, Katherine I. Morley, Richard Riley, Adam Timmis, Danielle Van der Windt, Ian Roberts, for the PROGRESS Partnership

PLOS Medicine

Differential effects of the Glasgow Coma Scale Score and its Components: An analysis of 54,069 patients with traumatic brain injury

Florence C.M. Reith, Hester F. Lingsma, Belinda J Gabbec, Fiona E. Leckye, Ian Roberts, Andrew I.R. Maas

International Journal of the Care of the Injured

A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])

Abda Mahmood, Ian Roberts, Haleema Shakur-Still

Trials

A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan

Abda Mahmood, Ian Roberts, Haleema Shakur-Still

Wellcome Open Research

Cost-effectiveness analysis of tranexamic acid for the treatment of traumatic brain injury, based on the results of the CRASH-3 randomised trial: a decision modelling approach

Jack Williams, Ian Roberts, Haleema Shakur-Still, Fiona E Lecky, Rizwana Chaudhri, Alec Miners

BMJ Global Health

Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results

Raoul Mansukhani, Lauren Frimley, Haleema Shakur-Still, Linda Sharples & Ian Roberts

Trials

Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial

Amy Brenner, Antonio Belli, Rizwana Chaudhri, Timothy Coats, Lauren Frimley, Sabariah Faizah Jamaluddin, Rashid Jooma, Raoul Mansukhani, Peter Sandercock, Haleema Shakur-Still, Temitayo Shokunbi & Ian Roberts On behalf of the CRASH-3 trial collaborators

Critical Care

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